Material that cannot be cut would make the ultimate bike lock

Found on New Scientist on Tuesday, 21 July 2020
Browse Science

Its inventors embedded ceramic spheres in aluminium foam to create a material that couldn’t be cut with angle grinders, power drills or water jet cutters.

“It’s pretty amazing,” says Miranda Anderson at the University of Stirling, UK, who worked on the project. Rather than just being a hard surface that resists external pressure, the material turns the force of the drill or cutting mechanism back on itself, as the ceramic spheres create vibrations that disrupt the external force. “It actually destroys the cutting blade through the sideways jerky vibrations that it creates, or it widens the water jet’s spray,” says Anderson.

Claims like these just make you want to mess around with the product to see if all that is really true.

New polymer easily captures gold extracted from e-waste

Found on Ars technica on Sunday, 28 June 2020
Browse Science

The researchers’ gold-scrubber is based on an organic compound called a porphyrin. Linked together in a polymer, it possesses lots and lots of little pores that, energetically, want to host a metal atom.

The researchers say the polymer costs about $5 per gram to produce, and that gram can capture $64 in gold. And since the polymer can be reused, it would be considerably cheaper than that over time, adding little to the overall cost of a recycling operation.

That will make it a lot easier to retrieve gold, assuming that the polymer itself is harmless and safe.

UK’s coronavirus science advice won’t be published until pandemic ends

Found on New Scientist on Sunday, 19 April 2020
Browse Science

“It’s disgraceful,” says Allyson Pollock, co-director of Newcastle University’s Centre of Excellence in Regulatory Sciences, UK, who was one of dozens of experts who signed a letter in The Lancet medical journal last month arguing that government advisors should be more transparent. “We ought to know who is advising the government,” she says.

“I think they should be sharing who the key people are and minutes of their meetings,” says Devi Sridhar, a public health scientist at the University of Edinburgh, UK, who also signed the letter published in The Lancet.

Hopefully they keep an eye on it, or it will simply be "forgotten" to be released.

Firm wielding Theranos patents asks judge to block coronavirus test

Found on Ars Technica on Wednesday, 18 March 2020
Browse Science

Back in 2018, the disgraced biotech company Theranos sold its patent portfolio to Fortress Investment Group, a division of Softbank. Now two of those patents have wound up in the hands of a little-known firm called Labrador Diagnostics—and Labrador is suing a company called BioFire Diagnostics that makes medical testing equipment.

As Stanford patent scholar Mark Lemley puts it, "this could be the most tone-deaf IP suit in history."

The patent system still needs to be fixed.

Permanent magnets stronger than those on refrigerator could be a solution for delivering fusion energy

Found on Phys.org on Sunday, 15 March 2020
Browse Science

Rare earth magnets have surprising and useful properties. They generate quite powerful fields for the magnets' small size, and these are "hard" fields that are almost unaffected by other fields nearby.

Permanent magnets have disadvantages, too. "You can't turn them off," Helander said, which means they can pull in anything they can attract within range.

It should be pretty obvious that you cannot turn off permanent magnets.

Trump could mandate free access to federally funded research papers

Found on Ars Technica on Saturday, 28 December 2019
Browse Science

The Trump White House is rumored to be working on a beefed-up open access mandate. The potential executive order would require all scientific papers that are based on federally funded research to be made available online free of charge as soon as they are published.

Supporters of the open access model question how much value traditional scientific publishers actually add. The peer-review process is typically carried out by working scientists on a volunteer basis. Meanwhile, you'd expect the Internet to reduce the costs of distributing scientific journals.

Paid by the public, free to the public. It's simple. If scientific magazines want research papers they can demand money for, they just should fund the research for those.

Gel that makes teeth repair themselves could spell the end of fillings

Found on New Scientist on Saturday, 31 August 2019
Browse Science

Tooth enamel can now be made to repair itself by applying a special gel. The product could save people from developing cavities that require dental fillings.

The gel stimulated the growth of new enamel, with microscopy revealing that it had the same highly ordered arrangement of calcium and phosphate crystals as regular enamel.

Expect that dentists will lobby against it in order to protect their income.

Gene editing wipes out mosquitoes in the lab

Found on BBC News on Tuesday, 25 September 2018
Browse Science

Researchers have used gene editing to completely eliminate populations of mosquitoes in the lab.

As the modified gene - which confers female infertility - spread, the caged populations crashed.

Prof Crisanti commented: "There is still more work to be done, both in terms of testing the technology in larger lab-based studies and working with affected countries to assess the feasibility of such an intervention.

They should consider to use this on ticks too; they are so very annoying and potentially dangerous too.

Doctors tried to lower $148K cancer drug cost; makers triple price of pill

Found on Ars Technica on Saturday, 21 April 2018
Browse Science

Taking just one pill a day could dramatically reduce costs to around $50,000 a year. And it could lessen unpleasant side-effects, such as diarrhea, muscle and bone pain, and tiredness. But just as doctors were gearing up for more trials on the lower dosages, the makers of the drug revealed plans that torpedoed the doctors’ efforts: they were tripling the price of the drug and changing pill dosages.

Imbruvica’s makers, Janssen and Pharmacyclics, have now gotten approval to sell four different tablets of varying strengths: 140mg, 280mg, 420mg, and 560mg. But the new pills will all be the same price—around $400 each—even the 140mg dose pill.

Free market and caitalism will fix everything? Doesn't look like it works so well. At some point you begin to enjoy the idea that those responsible for this should get cancer and be unable to pay for their own medicine. Then companies like unethical Goldman Sachs would quickly vanish from the face of earth. At least others do not play along with pharma companies and show them where the limits are.

Goldman Sachs asks in biotech research report: 'Is curing patients a sustainable business model?'

Found on CNBC on Sunday, 15 April 2018
Browse Science

"The potential to deliver 'one shot cures' is one of the most attractive aspects of gene therapy, genetically-engineered cell therapy and gene editing. However, such treatments offer a very different outlook with regard to recurring revenue versus chronic therapies," analyst Salveen Richter wrote in the note to clients Tuesday. "While this proposition carries tremendous value for patients and society, it could represent a challenge for genome medicine developers looking for sustained cash flow."

"GILD is a case in point, where the success of its hepatitis C franchise has gradually exhausted the available pool of treatable patients," the analyst wrote.

That makes you wonder if that "analyst" would think the same way if one of these "one shot cures" could end a disease which would make Salveen Jaswal Richter's life horrible. Maybe karma will teach her a harsh lesson.